Glossary entry

Spanish term or phrase:

GTPasa blanco inactiva unida a GDP

English translation:

inactive target GDP-bound GTPase

Added to glossary by Catalina Connon
Sep 7, 2005 13:14
18 yrs ago
2 viewers *
Spanish term

a su GTPasa blanco inactiva unida a GDP

Spanish to English Medical Medical (general) Molecular switches
Studies on guanine nucleotide exchange factors:

Las proteinas GEFs son capaces de unirse *a su GTPasa blanco inactiva unida a GDP* y promover la disasociacion del GDP para que esta pueda ser activada al unirse GTP.
Proposed translations (English)
5 +1 its inactive target GTPase bound to GDP
2 GTP-SASA

Discussion

Lorna Thomson (asker) Sep 7, 2005:
blanco? Hi! So, the translation of "blanco" here must therefore be "target"?? This was the point I was puzzling over; your answer has most helpfully confirmed the rest to me - thankyou so much!

Proposed translations

+1
1 hr
Selected

its inactive target GTPase bound to GDP

cycles between an active GTP-bound form and an inactive GDP-bound form. ...
In summary, the small GTPase Rheb is a direct target of

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Note added at 1 hr 37 mins (2005-09-07 14:52:25 GMT)
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or: inactive target GDP-bound GTPase

see: en.wikipedia.org/wiki/GTPase

...change of the GTPase from the active, GTP-bound form to the inactive, GDP-bound...
form by ... The GTPase is normally inactive. Upon receptor activation ...
Peer comment(s):

agree Muriel Vasconcellos
5 hrs
thanks Muriel
Something went wrong...
4 KudoZ points awarded for this answer. Comment: "Thanks so much for a great answer and also for the confirmation of a great answer :)"
20 mins
Spanish term (edited): GTP asa

GTP-SASA

Unido me parece que debe ser algo con "binding".Si haces otra pregunta, igual me animo...
Activación del terminal nervioso porque es invadido por un ...
En esta situación, existe en la membrana vesicular una GTP-asa (hidroliza GTP)
llamada Rab-3. Al hidrolizarse el GTP por la acción de esta enzima, ...
www.uc.cl/sw_educ/neurociencias/html/081.html - 7k - En caché - Páginas similares

DICCIONARIO ILUSTRADO DE TÉRMINOS MÉDICOS
Tuberina: una proteína codificada por un gen localizado en el cromosoma 16, que
se parece a la proteína activadora de la GTP-asa, GAP-3 y que forma un ...
www.iqb.es/diccio/t/tu.htm - 60k - En caché - Páginas similares

ATLAS DE DERMATOLOGIA
El síndrome está causado por mutaciones en el gen RAB27A,que codifica una pequeña
proteína GTP-asa (Rab27a) que está implicada en el mecanismo de transporte ...
www.iqb.es/dermatologia/atlas/griscelli/griscelli02.htm - 7k - En caché - Páginas similares

[PDF] ROLE OF cGMP AND IN VERTEBRATE PHOTORECEPTOR EXCITATION AND ADAPTATION
Formato de archivo: PDF/Adobe Acrobat
GDP for GTP. Transducin, a heterotrimeric protein that is composed of one. a,/3, and 3,-subunit each, ... Binder, g. M., Brewer, E., Bownds, M. D. 1989. ...
arjournals.annualreviews.org/doi/abs/10.1146/annurev.ph.54.030192.001101 - Páginas similares

Assessing functional divergence in EF-1α and its paralogs in ... - [ Traduzca esta página ]
GTP is hydrolyzed upon cognate codon–anticodon interaction between a tRNA and
mRNA in ... Solvent accessible surface area (ASA) is a widely used measure for ...
www.pubmedcentral.nih.gov/articlerender.fcgi?artid=165955 - Páginas similares

Alzheimer's presenilin 1 is a putative membrane receptor for rab ... - [ Traduzca esta página ]
GTP-bound rab proteins are associated with the cytoplasmic surface of transport
... so that it can bind rab proteins that have hydrolyzed their GTP. ...
hmg.oxfordjournals.org/cgi/content/full/9/2/303 - Páginas similares
Peer comment(s):

neutral Muriel Vasconcellos : That's not how it's written in English.
6 hrs
Ok, thx Muirel. Actually my confidence level was quite low...
Something went wrong...
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