Glossary entry

English term or phrase:

‘site-2’ membrane protease RasP

Spanish translation:

proteasa membranaria/de membrana de sitio 2 RasP

Added to glossary by Kepa S S O (X)
May 18, 2015 13:29
8 yrs ago
3 viewers *
English term

‘site-2’ membrane protease RasP

English to Spanish Science Biology (-tech,-chem,micro-) biochemistry
Saludos.
Por favor cuál sería la correcta traducción.
Gracias por su trabajo

Bacillus subtilis: from soil bacterium to super-secreting
cell factory

The secreted proteins of B. subtilis usually contain N-terminal
signal peptides that are important for export
from the cytoplasm. These signal peptides are composed
of three characteristic domains generally known as the
N-, H- and C-regions [13,20]. Arginine or lysine residues
in the N-region interact with the translocation machinery
and negatively charged phospholipids in the cell
membrane. The H-region comprises hydrophobic residues
that adopt an alpha-helical conformation, which is
necessary for the initiation of protein translocation
across the membrane. The C-region contains the recognition
and cleavage sites for signal peptidases (SPases)
that cleave off the signal peptide to release the mature
protein from the membrane during or shortly after
translocation [21]. Cleaved signal peptides are then
targeted for degradation by the ‘site-2’ membrane protease
RasP, and possibly other membrane-associated
proteases [20-22].
Change log

Jul 23, 2015 00:27: Kepa S S O (X) changed "Edited KOG entry" from "<a href="/profile/727081">Kepa S S O (X)'s</a> old entry - " ‘site-2’ membrane protease RasP"" to ""la proteasa de sitio 2 RasP, presente en la membrana""

Discussion

De hecho, escarbando un poquito más, parece que se trata de una proteasa intramembranaria (http://www.genetik.uni-bayreuth.de/page/24/Research).

PS: Si así lo desea, no tengo ningún problema con que se reabra la pregunta.
Hola. El adjetivo "membranaria" ("la proteasa membranaria de sitio 2 RasP"") satisfaría tu deseo de especificar que en este caso en concreto se trata de una proteasa asociada a la membrana.
¡Hola! La RasP, en principio, no tiene por qué estar en la membrana, por lo que especificar que está presente en la membrana en este caso en concreto me parece mejor que decir "de membrana", que parecería que siempre está en la membrana. ¡Un saludo!

Proposed translations

7 days
Selected

la proteasa de sitio 2 RasP, presente en la membrana

Un saludo.

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Note added at 9 days (2015-05-27 19:00:46 GMT) Post-grading
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Tras mirarme la bibliografía un poco más, cambio mi propuesta a: la proteasa membranaria de sitio 2 RasP<b/>. Saludos.
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4 KudoZ points awarded for this answer. Comment: "Muchas Gracias."
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